STRUCTURE-PRIMED EMBEDDING ON THE TRANSCRIPTION FACTOR MANIFOLD ENABLES TRANSPARENT MODEL ARCHITECTURES FOR GENE REGULATORY NETWORK AND LATENT ACTIVITY INFERENCE

Abstract Background Modeling of gene regulatory networks (GRNs) is limited due to a lack of direct measurements of genome-wide transcription factor activity (TFA) making it difficult to separate covariance and regulatory interactions.Inference of regulatory interactions and TFA requires aggregation of complementary evidence.Estimating TFA explicitl

Abstract Background Several lineages within the Crustacea conquered land independently during evolution, thereby requiring physiological adaptations for a semi-terrestrial or even a fully terrestrial lifestyle.Birgus latro Linnaeus, 1767, the giant robber crab or coconut crab (Anomura, Coenobitidae), is the largest land-living arthropod and inhabit

Abstract Progress in malaria control will rely on deployment and effective targeting of combinations of interventions, including malaria vaccines and perennial malaria chemoprevention (PMC).Several countries with PMC programmes have introduced malaria vaccination into their essential programmes on immunizations, but empirical evidence on the impact

Elaborate a strategic approach and actions of balanced development combined with fight against corruption and economic frauds.These problems in Faceguards the literature are studied mostly separately.Economists analyze practical deviations of the economic development policies from the requirements and principles of the modern and up-to-date economi

The foreground aim of medical education and the criterion of its effectiveness become the development of personal potential and implementation of professional component of the doctor to-be.The relevance of the issue is to acquire the methods of autonomous cognitive activity determined by the fact that during the period of study at the university, t